Esketamine Treatment


What is it?

Esketamine is a medication that is used to treat severe depression that has not responded to other treatments. Esketamine is a type of medication known as a glutamate receptor modulator and works by targeting the N-methyl-D-aspartate (NMDA) receptor in the brain.



The NMDA receptor is involved in the regulation of various functions in the brain, including mood, cognition, and pain perception. Esketamine is thought to work by blocking the NMDA receptor, which increases the availability of glutamate, a neurotransmitter that is involved in the regulation of mood and other cognitive processes. This increased availability of glutamate is believed to lead to the activation of other receptors and neuronal circuits that are involved in the regulation of mood, such as the AMPA receptor, which may help alleviate symptoms of depression.

Esketamine is administered via nasal spray and is typically used in conjunction with an oral antidepressant. It is typically prescribed for individuals with treatment-resistant depression, meaning that they have not responded to other treatments such as traditional antidepressants or psychotherapy.



It is important to note that esketamine can have significant side effects, including dissociation, dizziness, and sedation. As such, it is typically administered under the supervision of a healthcare professional in a medical setting.

Esketamine is a novel treatment option for individuals with severe depression that has not responded to other treatments, and it works by modulating the NMDA receptor and increasing the availability of glutamate in the brain.

Overall, if you or a loved one is struggling with severe depression and has not responded to other treatments, it may be worthwhile to explore the option of Esketamine treatment. The availability of Esketamine treatment and the specific protocols for its use may vary, so it is important to consult with our trusted professional at The Valens Clinic for personalized guidance.

To find out if Esketamine is right for you, please contact us or book your consultation online.


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